Abstract Purpose: COVID-19, caused by SARS-CoV2 virus is a contagious disease affecting millions of lives throughout the globe....

Abstract COVID-19 caused by the SARS-CoV-2 virus has become a global pandemic. 3CL protease is a virally encoded protein that is...

Ivermectin is an anti-parasitic agent that has shown promise against the virus in vitro. Its potential mechanism of action (MoA) in...

Safety, Pharmacokinetics, and Activity of High-Dose Ivermectin and Chloroquine against the Liver Stage of Plasmodium cynomolgi Infection...

Plasma ivermectin with and without coadministration of 10 mg/kg chloroquine reached maximum concentration of drug in serum (Cmax) at...

In macaques, coadministration of ivermectin (0.6 or 1.2 mg/kg) and chloroquine (10 mg/kg) for 7 days was safe and well-tolerated....

Abstract Despite rapid progress in genomic profiling in acute lymphoblastic leukemia (ALL), identification of actionable targets and...

RCT of 600 patients (400 symptomatic confirmed COVID-19 & 200 healthcare and household contacts) Group 1: 100 pts with mild/moderate...

Grouped countries into three different categories: Include ivermectin in prophylaxis Do not include ivermectin in prophylaxis Do not do...

gain, on the surface this looks promising, however going through the individual trials is essential, as the conclusions of any...

ADDENDUM 05/03/2021 – The EPIC Trial – RCT in Colombia [10] Clinical Question: What is the effect of ivermectin on duration of symptoms...

Ivermectin, a well-known anti-helmintic agent from the late-1970s, causes stimulation of gamma amino butyric acid (GABA)-gated-Cl−...

Abstract Ivermectin Invasive fungal infections cause 1.6 million deaths annually, primarily in immunocompromised individuals. Mortality...

SARS-CoV-2 is a newly emerged coronavirus that causes a respiratory disease with variable severity and fatal consequences. It was first...

Abstract Introduction COVID-19 cases are on surge; however, there is no efficient treatment or vaccine that can be used for its...

Background Ivermectin is an FDA-approved broad spectrum anti-parasitic agent, which was initially approved in humans in 1987 to treat...

Introduction Several methods for silencing neuronal electrical activity in behaving animals have been developed that could eventually be...

Highlights •Structural description of ivermectin binding to GlyRα3 at high-resolution •Binding of ivermectin expands the ion channel pore...

Ivermectin as a potential drug for treatment of COVID-19: an in-sync review with clinical and computational attributes Introduction...

its ability to suppress the virus in vitro. claimed that ivermectin in vitro had an inhibitory action on the novel Coronavirus, reducing...